Autophagy and Fasting for Life Extension.
Autophagy and Fasting for Life Extension.
The cellular 'cleanup' mechanism. A guide to time-restricted feeding that doesn't sacrifice performance.
Dr. Marcus Thorne
5 MIN READ
Cellular "housecleaning" for the long game.
Autophagy is the body's mechanism of "self-eating"—clearing out damaged cells to make room for new ones.
The 2026 View: We use DunedinPACE tracking to ensure your fasting protocols are actually slowing your pace of aging, not just causing muscle wasting.
The Bio-Mechanical Breakdown: Autophagy is regulated by the mTOR/AMPK pathway. When we suppress insulin through fasting, AMPK rises, triggering the body to recycle misfolded proteins and damaged organelles—essentially a "cellular detox".
Clinical Perspective: In 2026, we monitor DunedinPACE to ensure that fasting isn't causing "Biological Stress" that actually accelerates aging in the long run.